Adriamycin fda breast

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Medically reviewed by Carmen Fookes, BPharm. Last updated on April 21, Cytoxan, the branded version of cyclophosphamide has been discontinued in the United States. Generic versions of cyclophosphamide are still available. Adriamycin doxorubicin belongs to a class of cancer medicines called anthracycline antibiotics.

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Adriamycin (Doxorubicin) Chemotherapy for Breast Cancer

Adriamycin Dosage Guide - sciencesofa.info

Adriamycin doxorubicin —also known by the trade names Rubex and Doxil—is a chemotherapy drug that can slow or stop the growth of cancer cells. Adriamycin is commonly used to treat both early stage and metastatic breast cancer, usually in combination with other drugs. More specifically, Adriamycin is a type of anthracycline antibiotic that is an anti-tumor drug and is made from the bacterium Streptomyces. It can be beneficial in cancer treatment because it can inhibit the activity of an enzyme called topoisomerase-II after entering cancer cells and inserting itself into the DNA structure. This action makes cells unable to reproduce themselves.

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Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast Cancer

Doxorubicin trade name Adriamycin is a commonly used chemotherapy agent that is very effective in both Hodgkin and Non-Hodgkin lymphomas. It belongs to the class of chemotherapy drugs called anthracyclines. It is well recognized that doxorubicin may cause damage to the heart in some individuals. While other anthracyclines like epirubicin and mitoxantrone may also cause heart damage, the chances are more common with doxorubicin.

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If you are a consumer or patient please visit this version. Extravasation and Tissue Necrosis: Extravasation of doxorubicin can result in severe local tissue injury and necrosis requiring wide excision of the affected area and skin grafting. Immediately terminate the drug, and apply ice to the affected area [see Warnings and Precautions 5. Decrease the dose of doxorubicin in patients with elevated serum total bilirubin concentrations as follows:.

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